Proteines de fusion et methodes de clivage de ces proteines

Fusion proteins and methods of cleavage of such proteins

Abstract

The invention provides a method of processing recombinant proteins by using aspartate specific proteases.
L'invention concerne une méthode de traitement de protéines de recombinaison au moyen de protéases spécifiques d'aspartate.

Claims

Description

Topics

Download Full PDF Version (Non-Commercial Use)

Patent Citations (6)

    Publication numberPublication dateAssigneeTitle
    WO-0061768-A2October 19, 2000Yeda Research And Development Co. Ltd.Preparation of biologically active molecules
    WO-0073437-A1December 07, 2000Merck Frosst Canada & Co.Assays for caspase activity using green fluorescent proteins
    WO-0120989-A1March 29, 2001Mayo Foundation For Medical Education And ResearchProcedes et compositions therapeutiques utilisant des virus de la famille paramyxoviridae de recombinaison
    WO-0198455-A2December 27, 2001Smithkline Beecham CorporationProcede de preparation d'un polypeptide il-18 physiologiquement actif
    WO-0206458-A2January 24, 2002Chemicon International, Inc.Luciferases pouvant etre clivees de maniere specifique par une protease et procedes d'utilisation de ces luciferases
    WO-2004074488-A1September 02, 2004Biotecnol S.A., Vlaams Interuniversitair Instituut Voor Biotechnologie, Universiteit GentUtilisation d'enzymes caspases pour la maturation de fusions polypeptidiques de recombinaison par genie genetique

NO-Patent Citations (2)

    Title
    MERTENS N ET AL: "NEW STRATEGIES IN POLYPEPTIDE AND ANTIBODY SYNTHESIS: AN OVERVIEW", CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, LIEBERT, US, vol. 19, no. 1, February 2004 (2004-02-01), pages 99 - 109, XP008032571
    STENNICKE ET AL: "Biochemical characteristics of caspases-3, -6, -7 and -8", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 272, no. 41, 1997, pages 25719 - 25723, XP002146144, ISSN: 0021-9258

Cited By (4)

    Publication numberPublication dateAssigneeTitle
    US-7250274-B2July 31, 2007Zymogenetics, Inc.IL-21 production in prokaryotic hosts
    US-7622561-B2November 24, 2009Zymogenetics, Inc.IL-21 production in prokaryotic hosts
    US-7745176-B2June 29, 2010Zymogenetics, Inc.IL-21 production in prokaryotic hosts
    US-7767199-B2August 03, 2010Zymogenetics, Inc.Compositions of IL-21 produced in prokaryotic hosts